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Effect of Peripherally Inserted Central Catheters on CLABSI Rates in Adult ICU Patients
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Effect of Peripherally Inserted Central Catheters on CLABSI Rates in Adult ICU Patients

Brielle Bostow, Zachary Gruzs, Tehani Toi and Erin Kurth
2026
2026

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Abstract

In adult intensive care unit (ICU) patients, central line–associated bloodstream infections (CLABSI) remain a significant problem, contributing to increased mortality, prolonged hospital stays, and higher healthcare costs. Implementing evidence-based central line insertion and maintenance bundles reduces CLABSI rates; however, infections still occur due to prolonged catheter use, patient comorbidities, and variations in care practices (Centers for Disease Control and Prevention [CDC], 2024). Reported rates in U.S. ICUs are approximately 0.6–1.4 infections per 1,000 central line–days, with attributable mortality of 12%–25% (CDC, 2024; Agency for Healthcare Research and Quality [AHRQ], 2023). These infections are associated with longer hospital stays and higher healthcare costs compared with patients without CLABSI (AHRQ, 2023). Peripherally inserted central catheters (PICC) may lower the incidence of bloodstream infections compared with conventional central venous catheters (CVC), making the selection of the safest vascular access device essential for critically ill patients. Identifying the most appropriate device can significantly influence CLABSI rates, patient outcomes, and overall healthcare costs
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