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Journal article
Variable Temperature NMR Experiment Studying Restricted Bond Rotation
Journal of chemical education, Vol.97(5), pp.1425-1429
05/12/2020
Web of Science ID: WOS:000535226300030
Abstract
Nuclear magnetic resonance (NMR) spectroscopy has become a cornerstone tool for studying a variety of molecular features in advanced chemistry laboratories. In this experiment, students prepare a pyrrole-beta-amide via a one-pot, three-step synthesis and use NMR spectroscopy to confirm its molecular structure. In addition, variable temperature (VT) H-1 NMR spectroscopy is used to study the dynamic amide bond, a functional group with restricted rotation about the C-N bond. The VT NMR data allow the students to determine the coalescence temperature associated with the slow equilibrium at room temperature and the corresponding energy barrier (Delta G(double dagger)) for the restricted rotation about the C-N bond.
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Details
- Title
- Variable Temperature NMR Experiment Studying Restricted Bond Rotation
- Publication Details
- Journal of chemical education, Vol.97(5), pp.1425-1429
- Resource Type
- Journal article
- Publisher
- American Chemical Society (ACS); United States
- Number of pages
- 5
- Copyright
- Copyright © 2020 American Chemical Society and Division of Chemical Education, Inc.
- Identifiers
- WOS:000535226300030; 99380480677406600
- Academic Unit
- Hal Marcus College of Science and Engineering ; Chemistry
- Language
- English