Relationship between Depression and Blood Pressure and Pulse Rate in an Adolescent Clinic
Esraa M. Eloseily, James J. Burns, Raid Amin, John Bruyere, Steffi Khurana and Ali Kurady
Florida Pediatrician, Vol.42(3), pp.9-15
Summer 2022
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Abstract
Background: Depression is a risk factor for adult cardiovascular mortality with unclear pathophysiology. The literature on physiologic parameters related to depression is inconsistent and scant in adolescent patients.
Aim of the study: The purpose of this study is to determine if there is a relationship between depression and physiologic parameters including blood pressure (BP) and pulse rate (PR) in adolescents.
Methods: Adolescents with and without depression were compared to controls without depression for systolic BP, diastolic and PR using a two-way type III ANOVA.
Results: In depressed patients, there was significantly higher systolic BP percentiles (57.4 depressed versus 47.8 non-depressed; F (DF 1) = 4.48, p = 0.036), no difference in diastolic BP, and significantly higher PR in depressed males but not females (males depressed 86.7 vs. 72.1; F (DF 1) = 8.61, p =0.003).
Conclusion: Significantly higher systolic blood pressure percentiles in depressed patients vs. non-depressed patients and significantly higher pulse rates in depressed males but not females were found. These findings may lead to a greater understanding of the physiologic correlates of depressive psychopathology that have implications for subsequent development of cardiovascular disease