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Journal article
Intertester reliability of brachial artery flow-mediated vasodilation using upper and lower arm occlusion in healthy subjects
Vascular Health and Risk Management, Vol.4, pp.731-734
4
2008
PMCID: PMC2515434
PMID: 18827924
Web of Science ID: WOS:000210222500026
Abstract
The assessment of endothelial function as brachial artery fl ow-mediated vasodilatation is a widely used technique that determines the effect of risk factor intervention and may have the potential to predict the clinical benefit of antiatherogenic therapy. Previous studies suggest
that fl ow-mediated dilation is greater using the upper-arm occlusion technique, but no data are available to compare intertester reliability between technicians. This study was undertaken to compare the amount of hyperemia between upper and lower occlusion techniques and to determine reproducibility between testers. Nineteen healthy adults, ages 25 to 50, were included in the study. Brachial artery vasodilatation was measured 1 and 3 minutes post cuff deflation and was compared with the baseline and expressed as a percent change. There was a tester effect in the percent change in diameter across all measurements. The results of this study reveal inconsistencies between testers when using a blood pressure cuff to induce hyperemia for the assessment of endothelial function through brachial artery flow-mediated vasodilation. However, upper arm as compared to lower arm blood pressure cuff occlusion results in significantly greater hyperemia and vasodilatation, even though there was a difference in measurements between testers.
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- Title
- Intertester reliability of brachial artery flow-mediated vasodilation using upper and lower arm occlusion in healthy subjects
- Publication Details
- Vascular Health and Risk Management, Vol.4, pp.731-734
- Resource Type
- Journal article
- Publisher
- Dove Medical Press; Auckland
- Series
- 4
- Copyright
- 2008 Cosio-Lima et al, publisher and licensee Dove Medical Press Ltd.
- Identifiers
- WOS:000210222500026; 99380090652606600
- Academic Unit
- Movement Sciences and Health; Usha Kundu, MD College of Health
- Language
- English