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Journal article
Halogen-Mediated Electrophilic Cyclization Reactions
Organic chemistry : current research, Vol.2(2), e122
2013
Abstract
Reverse pharmacology or target-based drug discovery has created a need for an efficient synthetic process that can generate a library of small molecules, particularly heterocycles containing diverse chemical
functionalities and structures. More than 80% of the top drugs produced by US retailers containat least one heterocyclic unit. Heterocycles can improve pharmacological, toxicological and physiochemical properties
of a drug candidate by altering its lipophilicity, polarity, solubility and hydrogen bonding capability [2].
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- Title
- Halogen-Mediated Electrophilic Cyclization Reactions
- Publication Details
- Organic chemistry : current research, Vol.2(2), e122
- Resource Type
- Journal article
- Publisher
- Longdom Group SA; Belgium
- Number of pages
- 2
- Copyright
- Copyright: © 2013 Kesharwani T. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
- Identifiers
- 99380480677006600
- Academic Unit
- Hal Marcus College of Science and Engineering ; Chemistry
- Language
- English