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Half-Life of Polychlorinated Biphenyls in Occupationally Exposed Workers
Journal article   Peer reviewed

Half-Life of Polychlorinated Biphenyls in Occupationally Exposed Workers

Donald L. Phillips, Alexander B. Smith, Virlyn W. Burse, Gregory K. Steele, Larry L. Needham and W. Harry Hannon
Archives of environmental health, Vol.44(6), pp.351-354
11/01/1989
PMID: 2514628
Web of Science ID: WOS:A1989CJ80600003

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Abstract

In 1977 and 1985, serum polychlorinated biphenyl (PCB) concentrations were determined for 58 workers in a Bloomington, Indiana, factory that used polychlorinated biphenyls (PCBs) in capacitor manufacture until 1977. Less chlorinated PCBs were quantitated as Aroclor 1242, and more highly chlorinated PCBs were quantitated as Aroclor 1254. The median half-life was 2.6 y for Aroclor 1242 and 4.8 y for Aroclor 1254. However, the half-life varied inversely with the initial serum concentration. This pattern may be a result of continued low-level exposure, variation in the time of exposure, or enzyme induction by PCBs.

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