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Journal article
Environmentally benign process for the synthesis of 2,3-disubstituted benzo[b]thiophenes using electrophilic cyclization
Tetrahedron letters, Vol.54(33), pp.4373-4376
08/14/2013
Web of Science ID: WOS:000322287300005
Abstract
We have developed a greener process for the synthesis of 2,3-disubstituted benzo[b]thiophenes using electrophilic cyclization as a key step. Our method not only employs an environmentally friendly solvent ethanol, but also utilizes safe and inexpensive inorganic reagents to furnish the desired products in high yields under mild reaction conditions. In addition to iodo- and bromocyclization, chlorocylization was also successfully accomplished. (c) 2013 Elsevier Ltd. All rights reserved.
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Details
- Title
- Environmentally benign process for the synthesis of 2,3-disubstituted benzo[b]thiophenes using electrophilic cyclization
- Publication Details
- Tetrahedron letters, Vol.54(33), pp.4373-4376
- Resource Type
- Journal article
- Publisher
- Elsevier
- Number of pages
- 4
- Grant note
- 1039659 / National Science Foundation Major Research Instrumentation Award; National Science Foundation (NSF) 1039659 / Direct For Mathematical & Physical Scien; National Science Foundation (NSF); NSF - Directorate for Mathematical & Physical Sciences (MPS) Bard Summer Research Institute
- Copyright
- Copyright © 2013 Elsevier Ltd. All rights reserved.
- Identifiers
- WOS:000322287300005; 99380482397106600
- Academic Unit
- Chemistry; Hal Marcus College of Science and Engineering
- Language
- English