Excerpt from text - Over the past quarter-century, research on perinatal stem cells has expanded remarkably, reflecting their unique potential in regenerative and translational medicine. To capture the evolution of this field, a bibliometric analysis was conducted using the Web of Science (WOS) Core Research Topic (search date: 15 October 2025). The search strategy included major perinatal sources including umbilical cord, Wharton’s jelly, amniotic membrane, amniotic fluid, placenta, and fetal tissues as well as related secretome and extracellular vesicle studies. This comprehensive query yielded 55,639 publications, of which 40,131 were original research articles and proceedings papers. Notably, 33,273 publications appeared between 2000 and 2025, underscoring a steady and sustained rise in global scientific interest (Figure 1). The dominant research categories were Hematology and Immunology, followed by Cell Biology, Experimental Medicine, Tissue Engineering, and Oncology. These findings highlight not only the rapid expansion of perinatal stem cell research but also its broad interdisciplinary integration of fundamental biology to clinical translation and emerging biotechnologies.
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Editorial: Advances in perinatal stem cells research and applications
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Frontiers in cell and developmental biology, Vol.13