Metrics
111 Record Views
Journal article
Adenovirus and Respiratory Syncytial Virus in Chronic Sinusitis Using Polymerase Chain Reaction
The Laryngoscope, Vol.107(7), pp.923-925
07/1997
PMID: 9217132
Web of Science ID: WOS:A1997XJ29800017
Abstract
The aim of this study is to investigate the role of adenovirus and respiratory syncytial virus (RSV) in chronic sinusitis using the polymerase chain reaction (PCR) to assay for the viruses. PCR has proved to be more sensitive and specific than viral cultures and immunoassays in the detection of viruses. Adenovirus and RSV are among the most common viruses to cause upper respiratory tract infections. Sinus mucosa biopsies from 20 patients undergoing endoscopic sinus surgery were sterilely collected. Four specimens (20%) tested positive for RSV by PCR and none tested positive for adenovirus. Only one specimen tested positive for RSV and one for adenovirus by viral culture and immunofluorescence. Bacterial cultures tested positive in 40% of the 20 specimens. PCR can be used to detect RSV in patients with chronic sinusitis and PCR is more sensitive than viral culture and immunofluorescence techniques on sinus polyps and mucosa.
Related links
Details
- Title
- Adenovirus and Respiratory Syncytial Virus in Chronic Sinusitis Using Polymerase Chain Reaction
- Publication Details
- The Laryngoscope, Vol.107(7), pp.923-925
- Resource Type
- Journal article
- Publisher
- John Wiley & Sons, Inc
- Copyright
- © 1997 The Triological Society
- Identifiers
- WOS:A1997XJ29800017; 99380182440306600
- Academic Unit
- Public Health; Usha Kundu, MD College of Health
- Language
- English