A NOVEL ELECTROENCEPHALOGRAPHIC METHOD TO DETECT A BIOMARKER FOR MILD COGNITIVE IMPAIRMENT DUE TO ALZHEIMER'S DISEASE
Jameson Douglas Beach
University of West Florida
Master of Science (MS), University of West Florida
2012
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Abstract
A novel electroencephalographic (EEG) method was developed in order to detect a biomarker in a group of individuals with mild cognitive impairment due to Alzheimer's disease (MCI-AD). Six MCI-AD patients and eight healthy controls participated in the study. A power law model was used to predict the amplitude of the flash visual evoked potential-P2 (FVEP-P2) electrophysiological responses at five different intensities of light which were delivered via a stroboscopic lamp. Though the MCI-AD group exhibited FVEP-P2 latencies that were longer than those of age-matched controls, results of the study indicate that the power law model did not adequately distinguish MCI-AD participants from controls.