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Poster
Using phage to detect phospho-tau at position 217
University of West Florida Libraries
Student Scholar Symposium & Faculty Research Showcase (University of West Florida, Pensacola, Florida, 2021)
2021
Abstract
Alzheimer's Disease (AD) remains mostly undiagnosed in the early stages of the disease.
• By the time that AD is clinically observed, it is thought that the damage done to the brain is too severe to be reversible.
• There is significant research suggesting AD-mediated changes to tau exist such as phosphorylation, oxidation, proteolysis and others
• Furthermore, recent data have shown that hyperphosphorylation on the tau protein is a critical post-translational modification (PTM) in AD that appear to manifest up to decades before clinical diagnosis.
• Specifically, tau phosphorylated at the 217-threonine position has shown promising results in other studies
Details
- Title
- Using phage to detect phospho-tau at position 217
- Resource Type
- Poster
- Event
- Student Scholar Symposium & Faculty Research Showcase (University of West Florida, Pensacola, Florida, 2021)
- Contributors
- Dr. Rodney P. Guttman (Faculty Mentor)
- Publisher
- University of West Florida Libraries; Argo Scholar Commons
- Format
- 1 file; .pdf
- Copyright
- Permission granted to the University of West Florida Libraries to digitize and/or display this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires the permission of the copyright holder.
- Identifiers
- 99380090882006600
- Academic Unit
- Biology; Office of Undergraduate Research; 2021 Student Scholars Symposium and Faculty Research Showcase; Hal Marcus College of Science and Engineering
- Language
- English