Hexyne groups are important compounds for the production of many pharmaceuticals. Hexyne compounds are commercially available compounds, and are sold in differing orientations. The aim of this project is to utilize previously optimized methods for using hexanes, and apply these methods to optimize reactions of 1-hexyne to produce copper (I) 1-hexynide.</br>Using commercial grade 1-hexyne, this project aims to synthesize copper (I) 1-hexynide. The copper (I) acetylides family are characteristically yellow in color. Copper (I) acetylides are formed from a weak acid-base reaction. The same type of acid-base reaction can be applied to this fluorinated compound. Basic copper (I) oxide, Cu₂O, is reacted with the weakly acidic 1-hexyne in ethanol. Using a stronger acid as a catalyst, copper (I) 1-hexynide is synthesized.</br>Current methods for producing these compounds are tedious and time consuming. Many copper compounds are highly sensitive to air, and require air free conditions for the complete duration of production. Our methods eliminate the need for an air free filtration, making the process simpler. Many methods for making these compounds are environmentally unfriendly, as they use hazardous solvents. This “green” approach replaces these dangerous solvents with 95% ethanol, which is widely available and more environmentally friendly. By using affordable material and these simple methods, pharmaceutical companies could lower the prices of these medications, making them more available for those who need them.
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Title
Green Synthesis of Copper (I) 1-Hexynide
Resource Type
Poster
Event
Summer Undergraduate Research Program (University of West Florida, Pensacola, Florida, 08/2023)
Contributors
Arun T Royappa (Faculty Mentor)
Publisher
University of West Florida Libraries; Argo Scholar Commons
Format
pdf
Copyright
Permission granted to the University of West Florida Libraries to digitize and/or display this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires the permission of the copyright holder.