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Poster
EGFR-Targeted Phage Screening: Like Speed Dating, but for Science
University of West Florida Libraries
Summer Undergraduate Research Program (SURP) Symposium (University of West Florida, Pensacola, Florida, 08/2025)
08/2025
Abstract
This research aims to develop a novel cancer immunotherapy by engineering bacteriophages to target and block the epidermal growth factor receptor (EGFR). We created a model cancer cell line by introducing EGFR DNA into mammalian cells. Using a phage display library containing 10 million unique bacteriophages we screened (or you might say "will screen') for phages capable of binding to and blocking EGFR. Successful identification of EGFR-blocking phages could lead to the development of a new class of targeted cancer immunotherapy that harnesses the natural targeting capabilities of bacteriophages to disrupt cancer cell growth signals mediated by EGFR overexpression.
Details
- Title
- EGFR-Targeted Phage Screening: Like Speed Dating, but for Science
- Resource Type
- Poster
- Event
- Summer Undergraduate Research Program (SURP) Symposium (University of West Florida, Pensacola, Florida, 08/2025)
- Contributors
- Rodney Guttmann (Faculty Mentor)
- Publisher
- University of West Florida Libraries; Argo Scholar Commons
- Format
- pdf
- Copyright
- Permission granted to the University of West Florida Libraries by the author to digitize and/or display this information for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires the permission of the copyright holder.
- Identifiers
- 99381555074206600
- Academic Unit
- Biology; Summer Undergraduate Research Program 2025; Hal Marcus College of Science and Engineering
- Language
- English