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Poster
A review of CJD research regarding molecular function and genetic predispositions
University of West Florida Libraries
Student Scholar Symposium & Faculty Research Showcase (University of West Florida, Pensacola, Florida, 2021)
2021
Abstract
Creutzfeldt-Jakob disease (CJD) is the most common form of human transmissible spongiform encephalopathy, occurring at a rate of 1-2 per million. This disease is caused by the misfolding of a prion protein from its natural state (PrPᶜ) into a pathogenic state of the protein (PrPˢᶜ). The disease causes aggregation of amyloids in the brain that lead to symptoms akin to that of Alzheimer's disease and, in all cases, death. It has been found that the occurrence of this disease is associated with mutations in regions of PRNP gene that codes the prion protein, as well as changes in the genetic expression of many other genes. This state-of-the-art review compiles and analyzes the most recent research focusing on genetic predispositions related to CJD and how the effects of CJD on the body can be studied to find new diagnostic techniques. Also, it explores a recent case of interaction between CJD and COVID-19.
Details
- Title
- A review of CJD research regarding molecular function and genetic predispositions
- Resource Type
- Poster
- Event
- Student Scholar Symposium & Faculty Research Showcase (University of West Florida, Pensacola, Florida, 2021)
- Contributors
- Dr. Tiffany Jackman
- Publisher
- University of West Florida Libraries; Argo Scholar Commons
- Format
- 1 file; .pdf
- Copyright
- Permission granted to the University of West Florida Libraries to digitize and/or display this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires the permission of the copyright holder.
- Identifiers
- 99380090791906600
- Academic Unit
- Office of Undergraduate Research; 2021 Student Scholars Symposium and Faculty Research Showcase
- Language
- English