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Comparison of MMSE and ACTIVE methods for the identification of MCI
Conference presentation   Open access

Comparison of MMSE and ACTIVE methods for the identification of MCI

Heather Mutchie and Daniel W. Durkin
Annual Southeastern Student Mentoring Conference in Geriatrics and Gerontology, Athens, GA
2014

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Abstract

Mild Cognitive Impairment (MCI) is a term used to identify older adults with memory deficits but without dementia or significant related functional disability. Some research suggests that MCI is an introductory phase that may develop into more severe dementia. Ideally, multiple assessment tools should be used to determine MCI but this is often not practical in the clinical setting. Using secondary data on 2,045 participants from the Advanced Cognitive Training for Independent and Vital Elderly (ACTIVE) study, we compared two methods of determining MCI: the Mini Mental State Examination (MMSE) and composite scores from nine tests measuring memory, processing speed and reasoning (e.g . Hopkins Verbal Learning Test, Word Series Test). MCI designation was determined by using a cutoff score of <27 for the MMSE and by using a formula for the composite scores from the ACTIVE study. Chi-square analysis was used to compare MCI designation using the two methods and kappa values were calculated to assess agreement. Results showed that the two methods only agreed 68% of the time. The kappa statistic was .139 (p< .001) suggesting low agreement between the two measures. While the ACTIVE tests for MCI are more rigorous than the MMSE, the ACTIVE tests are significantly more time-consuming and not practical in the clinical setting. While it is possible that the MMSE may not be sensitive enough to detect MCI, it may still be useful as a screening tool. However, caution is warranted. Older adults identified with MCI by the MMSE should be referred for further testing.
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